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Biomark Med ; 15(4): 285-293, 2021 03.
Article in English | MEDLINE | ID: covidwho-1105969

ABSTRACT

Background: Troponin levels may be elevated in COVID-19 infection. The aim of this study was to the explore relation between troponin levels and COVID-19 severity. Materials, methods & Results: One hundred and forty consecutive patients with COVID-19 pneumonia were included. Diagnosis of COVID-19 pneumonia was based on positive chest computed tomography (CT) findings. Quantitative PCR test was performed in all patients. Only 74 patients were quantitative PCR-positive. Twenty four patients had severe CT findings and 27 patients had progressive disease. These patients had significantly lower albumin and higher ferritin, D-dimer, lactate dehydrogenase, C-reactive protein, and high-sensitivity cardiac troponin I (hs-cTnI). Conclusion: COVID-19 patients with severe CT findings and progressive disease had higher hs-cTnI levels suggesting the use of hs-cTnI in risk stratification.


Subject(s)
COVID-19 , Real-Time Polymerase Chain Reaction , SARS-CoV-2/metabolism , Tomography, X-Ray Computed , Adult , Aged , Biomarkers/blood , C-Reactive Protein/metabolism , COVID-19/blood , COVID-19/diagnosis , COVID-19/diagnostic imaging , COVID-19 Nucleic Acid Testing , Female , Ferritins/metabolism , Fibrin Fibrinogen Degradation Products/metabolism , Heart Diseases , Humans , L-Lactate Dehydrogenase/blood , Male , Middle Aged , Serum Albumin, Human/metabolism , Thorax/diagnostic imaging , Troponin I/blood
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